The purpose of this article is to describe a novel technique of multiphase fusion three-dimensional (3D) images Work Stations in patients with malignant pancreatobiliary obstruction.Multiphase fusion 3D images of CT arteriography, portovenography and hepatic venography combined with negative-contrast CT cholangiopancreatography can be done with enhanced multiphase CT scan using intravenous Depilatory Cream contrast agent at once.This technique may be feasible for one-stop evaluation of malignant pancreatobiliary obstruction.